Drug validation
Comprehensive preclinical drug validation to assess therapeutic potential and generate robust in vivo data for informed drug development decisions.
Preclinical drug validation overview
Preclinical drug validation is a critical step in evaluating the therapeutic potential of new drug candidates before further development. At IVRS, we provide specialized in vivo drug validation services designed to generate robust, reproducible data and support informed decisions throughout preclinical drug development.
IVRS provides a flexible preclinical drug validation platform supporting a wide range of therapeutic modalities, including small molecules, immunotherapies, cell and gene therapies, antibiotics, antiviral drugs, oncology therapies, anti-inflammatory agents, and metabolic and cardiovascular drugs. Our studies are tailored to each drug candidate, disease model and development objective, generating relevant in vivo data to support informed decisions throughout preclinical development.
Therapeutic activity assessment
Assess whether drug candidates demonstrate the intended biological and therapeutic activity in relevant preclinical models.
Safety and tolerability
Evaluate tolerability and potential safety signals to support informed decisions during preclinical drug development.
Pharmacokinetics & pharmacodynamics
Characterize drug exposure and pharmacological response through PK/PD studies to support dose selection and treatment strategy.
Mechanism of action
Investigate how drug candidates interact with molecular targets and biological pathways to better understand and validate their mechanism of action.
Key capabilities
- Therapeutic activity assessment
- Safety & tolerability
- PK / PD studies
- Mechanism of action
In vivo research services
Preclinical in vivo capabilities
01
In vivo imaging
Advanced in vivo imaging for longitudinal monitoring of disease progression and treatment response.
Read more →
02
Drug validation
Preclinical drug validation to assess therapeutic potential, biological activity and treatment response.
Read more →
03
Drug efficacy
In vivo drug efficacy studies to evaluate therapeutic response, dose effects and treatment outcomes.
Read more →
04
Biodistribution studies
Biodistribution studies to track drug delivery, tissue distribution and target-specific accumulation in vivo.
Read more →
05
Toxicology assessment
Preclinical toxicology studies to evaluate drug safety, tolerability and potential adverse effects.
Read more →
06
Preclinical study design
Customized preclinical study design tailored to disease models, therapeutic targets and drug development goals.
Read more →
Engage with us for journey to success
Do you want to learn more about our work and how we can help you?