Preclinical Study Design

Customized preclinical study design to select relevant in vivo models, endpoints and experimental strategies for robust drug development studies.

Preclinical study design overview

Successful preclinical studies require an experimental design aligned with the therapeutic candidate, biological question and development objectives. At IVRS, we combine scientific expertise with in vivo research experience to design tailored studies using relevant disease models, endpoints and read-outs, generating robust and decision-relevant data for preclinical drug development.

IVRS supports preclinical programs from initial study planning through model selection, endpoint definition and data collection strategies. Each study is tailored to the therapeutic candidate and development objectives to maximize scientific value while improving study efficiency.

Study strategy & experimental design

Define study objectives, experimental groups, dosing strategies and timelines aligned with the drug development question.

Model selection

Select relevant in vivo disease models based on therapeutic targets, mechanisms and study objectives.

Endpoints & read-outs

Define meaningful biological endpoints and quantitative read-outs to generate robust, decision-relevant data.

Imaging-integrated study design

Integrate longitudinal in vivo imaging into study design to monitor biological changes over time and maximize information from each experiment.

Key capabilities

In vivo research services

Preclinical in vivo capabilities

In vivo imaging

Advanced in vivo imaging for longitudinal monitoring of disease progression and treatment response.

Drug validation

Preclinical drug validation to assess therapeutic potential, biological activity and treatment response.

Drug efficacy

In vivo drug efficacy studies to evaluate therapeutic response, dose effects and treatment outcomes.

Biodistribution studies

Biodistribution studies to track drug delivery, tissue distribution and target-specific accumulation in vivo.

Toxicology assessment

Preclinical toxicology studies to evaluate drug safety, tolerability and potential adverse effects.

Preclinical study design

Customized preclinical study design tailored to disease models, therapeutic targets and drug development goals.

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